| dc.description.abstract |
Basal forebrain cholinergic neurons provide cholinergic input to the entire cortical mantle. Hence, these neurons have significant roles in processes such as learning, memory, attention, and the general arousal state. Previous studies by the project leader has identified two types of basal forebrain cholinergic neurons based on their physiological properties in vitro. These neurons were referred to as early- and late-firing neurons as their action potential delay was the determining parameter for distinguishing them into two electrophysiological subtypes. The current project aims to understand whether these electrophysiological differences have any morphological correlates. It is hoped that any morphological correlates found would help to identify further differences among these neurons in guiding future research and potential clinical implications. |
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